MIS is a business degree, with a minor emphasis on computer science. The IT degree will train you to be a technical support professional.
In order to decide which degree you want, imagine the job that you would like when you graduate. If you want to be making decisions about marketing, finance, and accounting while working as a liaison with computer personnel, then choose MIS. If you like to install hardware/software, set up and administer a network, manage a web server, do simple web programming, and administer a database, then choose the IT degree.